2-D PAGE Map Analysis -

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Editeur : Springer Us, New York, N.Y.

Langue : Anglais

Parution : 31/07/2016

Format : Moyen, de 350g à 1kg

Nombre de pages : 348

Expédition : 655

Dimensions : 25.4 x 17.8 x 1.9

ISBN : 1493949497

Résumé :

Sources of Experimental Variation in 2D-Maps: The Importance of Experimental Design in Gel-Based Proteomics.-?Decoding 2D-Maps by Autocovariance Functions.-?Two-Dimensional Gel Electrophoresis Image Analysis via Dedicated Software Packages.- Comparative Evaluation of Software Features and Performances.-?Image Pretreatment Tools I: Algorithms for Maps Denoising and Background Subtraction Methods.-?Image Pretreatment Tools II: Normalization Techniques for 2DE and 2D-DIGE.-?Spot Matching of 2-DE Images Using Distance, Intensity, and Pattern Information.- Algorithms for Warping of 2D-PAGE Maps.-?2-DE Gel Analysis: The Spot Detection.-?GENOCOP Algorithm and Hierarchical Grid Transformation for Image Warping of Two Dimensional Gel Electrophoretic Maps.-?Detection and Quantification of Protein Spots by Pinnacle.-?A Novel Gaussian Extrapolation Approach for 2D Gel Electrophoresis Saturated Protein Spots.-?Multiple Testing and Pattern Recognition in 2DE Proteomics.-?Chemometric Multivariate Tools for Candidate Biomarkers Identification: LDA, PLS-DA, SIMCA, Ranking-PCA.-?The Use of Legendre and Zernike Moment Functions for the Comparison of 2D-PAGE Maps.-?Nonlinear Dimensionality Reduction by Minimum Curvilinearity for Unsupervised Discovery of Patterns in Multidimensional Proteomic Data.-?Differential Analysis of 2D-Maps by Pixel-Based Approaches.

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Biographie:
Dr Elisa Robotti, PhD Dip. Scienze e Innovazione Tecnologica Universit? del Piemonte Orientale Viale Michel 11 15121 Alessandria Tel: +39 0131 360272 Fax: +39 0131 360250 e-mail: elisa.robotti@mfn.unipmn.it Emilio Marengo Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy. marengoe@tin.it

Sommaire:

Sources of Experimental Variation in 2D-Maps: The Importance of Experimental Design in Gel-Based Proteomics.-?Decoding 2D-Maps by Autocovariance Functions.-?Two-Dimensional Gel Electrophoresis Image Analysis via Dedicated Software Packages.- Comparative Evaluation of Software Features and Performances.-?Image Pretreatment Tools I: Algorithms for Maps Denoising and Background Subtraction Methods.-?Image Pretreatment Tools II: Normalization Techniques for 2DE and 2D-DIGE.-?Spot Matching of 2-DE Images Using Distance, Intensity, and Pattern Information.- Algorithms for Warping of 2D-PAGE Maps.-?2-DE Gel Analysis: The Spot Detection.-?GENOCOP Algorithm and Hierarchical Grid Transformation for Image Warping of Two Dimensional Gel Electrophoretic Maps.-?Detection and Quantification of Protein Spots by Pinnacle.-? A Novel Gaussian Extrapolation Approach for 2D Gel Electrophoresis Saturated Protein Spots.-?Multiple Testing and Pattern Recognition in 2DE Proteomics.-?Chemometric Multivariate Tools for Candidate Biomarkers Identification: LDA, PLS-DA, SIMCA, Ranking-PCA.-?The Use of Legendre and Zernike Moment Functions for the Comparison of 2D-PAGE Maps.-?Nonlinear Dimensionality Reduction by Minimum Curvilinearity for Unsupervised Discovery of Patterns in Multidimensional Proteomic Data.-?Differential Analysis of 2D-Maps by Pixel-Based Approaches.