Data Mining Techniques for the Life Sciences -

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Résumé :

Update on Genomic Databases and Resources at the National Center for Biotechnology Information.-?Protein Structure Databases.-?The MIntAct Project and Molecular Interaction Databases.-?Applications of Protein Thermodynamic Database for Understanding Protein Mutant Stability and Designing Stable Mutants.-?Classification and Exploration of 3D Protein Domain Interactions using Kbdock.-?Data Mining of Macromolecular Structures.-?Criteria to Extract High Quality Protein Data Bank Subsets for Structure Users.-?Homology-based Annotation of Large Protein Datasets.-?Identification and Correction Of Erroneous Protein Sequences in Public Databases.-?Improving the Accuracy of Fitted Atomic Models in Cryo-EM Density Maps Of Protein Assemblies Using Evolutionary Information From Aligned Homologous Proteins.-?Systematic Exploration of an Efficient Amino Acid Substitution Matrix, MIQS.-?Promises and Pitfalls of High Throughput Biological Assays.-?Optimizing RNA-seq Mapping with STAR.-?Predicting Conformational Disorder.-?Classification of Protein Kinases Influenced By Conservation of Substrate Binding Residues.-?Spectral-Statistical Approach for Revealing Latent Regular Structures in DNA Sequence.-?Protein Crystallizability.-?Analysis and Visualization of ChIP-Seq and RNA-Seq Sequence Alignments using ngs.plot.-?Data Mining with ontologies.-?Functional Analysis of Metabolomics Data.-?Bacterial Genomics Data Analysis in the Next-Generation Sequencing Era.-?A Broad Overview of Computational Methods for Predicting the Pathophysiological Effects of Non-Synonymous Variants.-?Recommendation Techniques for Drug-Target Interaction Prediction and Drug-Repositioning.-?Protein Residue Contacts and Prediction Methods.-?The Recipe for Protein Sequence-Based Function Prediction and its Implementation in the Annotator Software Environment.-?Big Data, Evolution, and Metagenomes: Predicting Disease from Gut Microbiota Codon Usage Profiles.-?Big Data in Plant Science: Resources and Data Mining Tools for Plant Genomics and Proteomics.

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