Inorganic Polyphosphates -

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Présentation Inorganic Polyphosphates de Format Relié
- Livre Médecine, Pharmacie, Paramédical, Médecine vétérinaire

Livre Médecine, Pharmacie, Paramédical, Médecine vétérinaire - 01/06/2022 - Relié - Langue : Anglais

Editeur : Springer International Publishing Ag

Langue : Anglais

Parution : 01/06/2022

Format : Moyen, de 350g à 1kg

Nombre de pages : 200

Expédition : 471

Dimensions : 24.1 x 16.0 x 1.7

ISBN : 3031012364

Résumé :
This volume focuses on the biomedical aspects of inorganic polyphosphates, a family of unique bio-inorganic polymers. In recent years, great advances have been made in understanding the development, metabolism, and physiological role of inorganic polyphosphates. These energy-rich polymers, which consist of long chains of phosphate units, are evolutionary old molecules. The acidocalcisomes, conserved organelles from bacteria to humans, as well as the mitochondria play a central role in polyphosphate production and storage. Polyphosphates have been assigned multiple functions, some of which are closely related to medically important processes, such as blood coagulation and fibrinolysis, energy metabolism, cell cycle regulation, apoptosis, chaperon function, microvascularization, stress response, neurodegeneration and aging. The development of bioinspired polyphosphate particles, in combination with suitable hydrogel-forming polymers enabled the development of new strategies in regenerative medicine, in particular for hard and soft tissue repair, but also in drug delivery and antimicrobial defense. This book not only highlights the basic research in this area, but also discusses possible applications. Therefore, it appeals to scientists working in cell biology, biochemistry, and biomedicine and practicioners alike.

...

Biographie:

Werner E.G. M?ller is a university professor at the Medical Center of the University Mainz and head of an ERC Advanced Investigator Grant Group. For his pioneering work in enzymology, molecular biomineralization, and molecular evolution, he has received nearly 20 national and international awards, including the Federal Cross of Merit, First Class of Germany. His current research focuses on applying this knowledge to the development of energy-delivering biopolymers/polyphosphates based (nano)biomaterials for regenerative medicine (bone and cartilage repair, wound healing, etc.). He has more than 1,200 publications (h-index: 88 [ISI-WOS]) and 20 granted patents. In addition to his ERC Advanced Investigator Grant, he has received three ERC-PoC Grants on repair/regeneration of bone, cartilage and blood vessels. He is/was also the coordinator of further European Grants as well as national DFG, BMWi and BMBF Grants.

Heinz C. Schr?der is a chemist and physician and gained his doctorate in both disciplines with distinction. 1982-1983 Liebig fellowship at the Max Planck Institute for Biophysical Chemistry in G?ttingen, Germany, and 1988 fellowship at the National Cancer Center Research Institute, Tokyo, Japan. Since 1985 he has been a professor at the University Medical Center of Johannes Gutenberg University Mainz. His present research interests include the investigation of the physiological function of polyphosphates, as well as the formation of biogenic nanoparticles, and their biomedical application. H. C. Schr?der has received several awards and is author or co-author of more than 500 scientific publications (h-index: 64 [ISI-WOS]). Together with Prof. Dr. W.E.G. M?ller, he was involved as a coordinator or partner in more than 20 EU projects.

Patrick Suess is a biochemist and cell biologist. In 2018 he was awarded the Texas A&M Roozbeh Arianpour Memorial Scholarship in Biology, and in 2020 was awarded a NIH/NHLBI-funded T32 training fellowship in molecular and translational hematology. Since 2018 he has been a postdoctoral fellow in the lab of Jim Morrissey at the University of Michigan, Ann Arbor. His current research focuses on the physiological roles of polyphosphates released from activated platelets. ...

Sommaire:
This volume focuses on the biomedical aspects of inorganic polyphosphates, a family of unique bio-inorganic polymers. In recent years, great advances have been made in understanding the development, metabolism, and physiological role of inorganic polyphosphates. These energy-rich polymers, which consist of long chains of phosphate units, are evolutionary old molecules. The acidocalcisomes, conserved organelles from bacteria to humans, as well as the mitochondria play a central role in polyphosphate production and storage. Polyphosphates have been assigned multiple functions, some of which are closely related to medically important processes, such as blood coagulation and fibrinolysis, energy metabolism, cell cycle regulation, apoptosis, chaperon function, microvascularization, stress response, neurodegeneration and aging. The development of bioinspired polyphosphate particles, in combination with suitable hydrogel-forming polymers enabled the development of new strategies in regenerative medicine, in particular for hard and soft tissue repair, but also in drug delivery and antimicrobial defense. This book not only highlights the basic research in this area, but also discusses possible applications. Therefore, it appeals to scientists working in cell biology, biochemistry, and biomedicine and practicioners alike.

...

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Inorganic Polyphosphates -

Avis sur Inorganic Polyphosphates de Format Relié - Livre Médecine, Pharmacie, Paramédical, Médecine vétérinaire

Présentation Inorganic Polyphosphates de Format Relié - Livre Médecine, Pharmacie, Paramédical, Médecine vétérinaire

Présentation Inorganic Polyphosphates de Format Relié
- Livre Médecine, Pharmacie, Paramédical, Médecine vétérinaire