Mitosis -

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Résumé :
Mitosis - division of a cell to produce two daughter cells - is a complicated process that must be highly coordinated to ensure events such as chromosome separation take place at the right time and in the right order. This book provides a state-of-the-art examination of the mechanics of mitosis, how the process is regulated, and the different checkpoints and quality-control steps involved.

Biographie:
how the spindle microtubules nucleate, elongate, pause, and shrink...

Sommaire:
Virtually every cell in a living organism contains an identical set of chromosomes thanks to mitosis, a complex process involving hundreds of proteins and regulatory steps that ensures duplicated chromosomes are segregated equally into each daughter cell when a cell divides. Errors in this process can lead to genomic instability and are associated with cancer and other diseases.
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers both historical and recent developments in our understanding of mitosis and its regulation. The contributors describe how sister chromatids attach to one another and to the spindle apparatus...