Optimization in HPLC - Stavros Kromidas

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Résumé :
This handy guide provides detailed practical information for HPLC practitioners of all skill levels, enabling them to optimize the performace of their HPLC/UHPLC system for a wide range of analytical tasks.

Biographie:
Stavros Kromidas, PhD, works as an independent consultant for analytical chemistry, based in Saarbrucken (Germany). For more than 20 years he has regularly held lectures and training courses on HPLC, and has authored numerous articles and several books on various aspects of chromatography. He is the founder of NOVIA GmbH, a provider of professional training and consulting in analytical chemistry, and served as its CEO until 2001.

Sommaire:
PART 1: OPTIMIZATION STRATEGIES FOR DIFFERENT MODES AND USES OF HPLC Working under regulatory constraints Reverse phase gradient methods 2-Dimensional chromatography HILIC LC-MS Biomolecules Supercritical fluid chromatography Chiral substances Column selection for small molecules Optimization based on analyte structure PART 2: COMPUTER-AIDED OPTIMIZATION ChromSword DryLab Fusion QbD Quality by Design approaches to determine the robust range PART 3: CURRENT CHALLENGES FOR HPLC USERS IN INDUSTRY Big Chemistry Big Analytical Service Providers Small Analytical Service Providers PART 4: CURRENT CHALLENGES FOR HPLC EQUIPMENT SUPPLIERS Thermo Fisher Scientific Agilent Shimadzu Waters Knauer