Combinatorial Chemistry - Willi Bannwarth

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Résumé :
The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. Experimental details and complete reaction data [...] are a constant theme running through this work (Angewandte Chemie) Recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope (Journal of the American Chemical Society)

Sommaire:
Purification Principles in High-Speed Solution Phase Synthesis (S. Weinbrenner, C. Tzschucke) Linkers for Solid-Phase Organic Synthesis (SPOS) and Combinatorial Approaches on Solid Support (W. Bannwarth) Cyclative Cleavage - A Versatile Concept in Solid-Phase Organic Chemistry (J. Pernerstorfer) C-C Bond Forming Reactions (W. Brill, G. Papeo) Combinatorial Synthesis of Heterocycles (E. Felder, A. Marzinzik) Polymer-Supported Reagents: Preparation and Use in Parallel Organic Synthesis (B. Hinzen, M. Hahn) Encoding Strategies for Combinatorial Libraries (B. Hinzen) Automation and Devices for Combinatorial Chemistry and Parallel Organic Synthesis (C. Zechel) Computer-Assisted Library Design (A. Dominik) Assays for High Throughput Screening in Drug Discovery (C. Apfel, T. Enderle) Appendix: Cheminformatics and Web Resources for Combinatorial Chemistry