Psychoneuroendocrine Dysfunction - Donald, Alexander G.

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Résumé :
There is no area in medicine that has affected biological psychiatry more pro? 15 years in en? foundly than the developments that have occurred in the last docrinology and more specifically in neuroendocrinology. In the 1960s, the regulation of endocrine function was considered to rest primarily in the feed? back system between the pituitary and the secretions of various target organs. In R. H. Williams' Fourth Edition of the Textbook of Endocrinology published in 1968, the chapter on neuroendocrinology did refer to the median eminence gland with a relatively brief mention of various releasing factors that were the subject of ongoing studies. Only six years later, in the Fifth Edition published in 1974, Seymour Reichlin's chapter on neuroendocrinology listed nine specific hypothalamic releasing factors of which three had already been isolated and purified and thus were referred to as hormones. Most recently in the current Sixth Edition, published in 1981, the chapter on neuroendocrinology contains a detailed description of the physiology of the various hypothalamic releasing factors and hormones, but also significant emphasis is given to the various neurotransmitters that have been shown to regulate the synthesis and release of these important hypothalamic hormones. In addition, there appeared for the first time in this classic textbook a chapter on psychoendocrinology. One may wonder why there is so much interest not only in endocrinology but more recently in psychology and psychiatry about psychoneuroendocrine It has been known for some time function. Several reasons may be suggested.

Sommaire:
Psychoneuropharmacology and Neuroendocrinology: Implications in Neuropsychiatric Research.- 1. Neuroendocrinology and Brain Peptides: An Emerging new Frontier in Neurobiology.- 2. Neuropharmacological Influences on Hypothalamic-Pituitary Secretion.- 3. TRH Interactions with Cholinergic Mechanisms and Consequent Therapeutic Implications.- 4. Calcitonin as an Anorectic Agent.- 5. Gonadal Dysfunction in Anorexia Nervosa: A Minireview.- 6. Abnormalities in Anorexia Nervosa of Dexamethasone Suppression Test and Urinary MHPG Suggest a Norepinephrine Hypothesis.- 7. Role of Brain Monoamines and Peptides in the Regulation of Male Sexual Behavior.- 8. Plasma Catecholamines as an Index of a Neuroendocrine Response.- 9. Nonspecific Pituitary Responses to Hypothalamic Hormones in Basic and Clinical Research.- 10. Neuroendocrine Studies in Huntington's Disease.- 11. ACTH4-10: Effects on Pavlovian Conditioning.- 12. ACTH4-10 and Memory in Psychiatric Patients.- 13. Vasopressin in Neuropsychiatry Disorders.- 14. Endogenous Opiate Systems May Modulate Learning and Memory.- 15. Possible Role of Opioids in Mental Disorders: Present State of Knowledge.- 16. Endogenous Opioid Peptides in Schizophrenia and Affective Disorders.- 17. Changes of Brain Monoamines in the Animal Model for Depression.- 18. Psychoendocrinology of Depression.- 19. Neuroendocrine Dysfunction in Subtypes of Depression.- 20. Biological Tests in the Diagnosis and Treatment of Affective Disorders.- 21. The Dexamethasone Suppression Test in Clinical Psychiatry.- 22. The TRH Test in the Diagnosis of Affective Disorders and Schizophrenia.- 23. Aspects of Thyroid Axis Function in Depression: A Review.- 24. Chrononeuroendocrinology of Depression: An Interpretation of Neuroendocrine Rhythms on the Basis of Pharmacological Studies.- 25. Alterations in Circadian Secretion of Pituitary and Pineal Hormones in Affective Disorders.- 26. A Study of Circadian Variation of Platelet Serotonin Uptake and Serum Cortisol in Patients with Major Depression.- 27. Neuroendocrine Evaluation of Catecholaminergic Function in Man: Application to Research in Psychiatry and Neurology.- 28. Neuroendocrine Studies in Schizophrenia.- 29. Exogenous Peptides and Schizophrenia.- 30. Hormonal Responses to D-Amphetamine in Schizophenia.- 31. Neuroleptics and Prolactin: A Second Look.- 32. Neuroendocrine Changes during the Course of Neuroleptic Treatment of Schizophrenic Patients.- 33. Effects of Long-Term Neuroleptic Treatment on Serum Levels of Prolactin, TSH, LH, and Norepinephrine and on ?-Adrenergic and Dopaminergic Receptor Sensitivity: Relations to Tardive Dyskinesia.- 34. Central Nervous System and Pituitary Dopaminergic Defects in Hyperprolactinemic States.