Selenium -

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Résumé :
Although toxic in large doses, selenium is an essential trace mineral in the animal diet and in some plants. It has a role in making antioxidant enzymes and a particular role in the functioning of the thyroid gland. This volume examines the chemical activity of selenium and its functional health effects eg towards cancers, in the heart and brain. It also covers other areas such as functional food enrichment, whole body metabolism, and the effects of selenium deficiency on health. Part of The Food and Nutritional Components in Focus series, this edited volume pools knowledge across scientific disciplines in a way that increases its applicability to a wide range of audiences. Victor Preedy's own distinguished career in nutritional science has made him a prolific author of research articles and books in this area, and this project fills a gap in providing comprehensive synopses of food substances. Chemists, analytical scientists, forensic scientists, food scientists, as well as course lecturers will all benefit from this interdisciplinary title written by international experts in this area.

Biographie:
Victor R. Preedy is a senior member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry; Hon). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981 and in 1992, he received his Membership of the Royal College of Pathologists. Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. During his career, Professor Preedy has worked at the National Heart Hospital (part of Imperial College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. He is a leading expert on nutritional and food sciences and has a long standing interest in how food, food quality, nutrition and diet affect wellbeing and health. He has lectured nationally and internationally. To his credit, Professor Preedy has over 600 publications, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews, books and volumes.

Sommaire:
The Chemistry of Selenium; Biochemistry and Molecular Biology of Selenoproteins; Synthesis of Organoselenium Derivatives of Biological Relevance; Chemistry and Activity of Selenium Dioxide and Selenite Ions; Chemistry and Biochemistry: Selenium species in fish;Current Analytical Strategies and Techniques related to Selenoproteins in Foods; Focus on determination of selenocysteine and selenomethionine in foodstuffs of animal origin by 2D size-exclusion reversed-phase HPLC-ICP MS; Some aspects of selenium determination employing solid phase extraction and atomic absorption spectrometry; Identification of selenometabolites in animals and plants by mass spectrometry; Bioavailability of selenium and selenium compounds in foodstuff by in-vivo testing; Bioavailability of selenium and selenium compounds in foodstuff by in-vitro testing; Assay of selenium in dietary supplements; Selenium as a Modulator of Fourier Transform Infrared Spectra in Cancer; Selenium Status Assessment by Questionnaire in Clinical and Cardiovascular Studies; Functional Foods enriched in Selenium; Selenium in Parenteral Nutrition; Biofortification of Fruit and Vegetables with Selenium; Biofortification of Legumes with Selenium in Semiarid Conditions; Selenium in Saliva and Impact on Health; Selenohomolanthionine and its potential use in medicine and nutrition; Therapy with selenium cocktails and co-use of lycopene and selenium; Selenium and cancer; Selenium and Skin Cancer; Selenium and Cancer Metastasis; The Selenium and Vitamin E Cancer Prevention Trial; Selenium in Autoimmune Thyroiditis; Selenoproteins in Brain; Selenoprotein H in Neuronal Cells; Current Clinical Perspectives of Selenium in Vascular Function and Cardiomyopathy; Selenium and the Heart; Selenium and Kashin-Beck disease; Selenium, the placenta and trophoblast mitochondrial oxidative stress; Selenium and Antioxidant Microgels.