Stem Cells and CNS Development -

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Résumé :
Stem Cells and CNS Development critically reviews recent findings on stem cells, their involvement in neurogenesis and gliogenesis, and the therapeutic implications of these findings. It defines by consensus the classes of stem cells in the nervous system, compares their similarities and differences, discusses the gains made in identifying human homologs of neural stem cells, and describes how these cells are beginning to be used for therapeutic purposes. Comprehensive and cutting-edge, this book provides all developmental scientists and neurobiologists not only an authoritative account of the current results in neural stem cell research, but also an incisive review of the rapidly emerging therapeutic uses of stem cells.

Sommaire:
Defining Neural Stem Cells and Their Role in Normal Development of the Nervous System Sally Temple Multipotent Stem Cells in the Embryonic Nervous System John A. Kessler, Mark F. Mehler, and Peter C. Mabie Multipotent Stem Cells in the Adult Central Nervous System Luca Bonfanti, Angela Gritti, Rossella Galli, and Angelo L. Vescovi Glial Characteristics of Adult Subventricular Zone Stem Cells Daniel A. Lim and Arturo Alvarez-Buylla Neuronal Restricted Precursors Giri Venkatraman and Marla B. Luskin Glial Restricted Precursors Mark Noble and Margot Mayer-Pr?schel PNS Precursor Cells Tanya A. Moreno and Marianne Bronner-Fraser Neural Progenitor Cells of the Adult Human Brain Steven A. Goldman ES Cells and Neurogenesis John W. McDonald Mobilizing Endogenous Stem Cells Theo D. Palmer, Sophia Colamarino, and Fred H. Gage Transplant Therapy Barbara A. Tate, Kate A. Bower, and Evan Y. Snyder Drug Discovery and Gene Discovery Alexander Kamb and Mahendra S. Rao Appendix A: Neural Stem Cell Companies Appendix B: Stem Cells and Transplants Appendix C: Patents and Stem Cells Appendix D: Stem Cells and US Federal Guidelines About the Authors