Transgenic Insects: Techniques and Applications - Mark Quentin Benedict

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Résumé :
Insect transgenesis promises improvements in agriculture, pharmaceuticals and public health. Many important insects can now be routinely transformed with effectors that have useful applications. Agriculture presents the largest market for transgenic insects and has a foundational history of success with sterile insect technique for control of pests including Mediterranean fruit flies and screwworms. Biotechnology will contribute superior markers, suppressible sterility and sex-conversion. Public health is also seeing transgenic mosquitoes developed which suppress natural populations and are incapable of transmitting disease. Experts in the field will contribute their insights into the latest technology and its applications. Authors will also consider the larger risks, social and economic aspects of transgenic insects whose value must be proven in political, regulatory and public acceptance arenas.

Biographie:
Mark Quentin Benedict, University of Perugia, Italy

Sommaire:
1. Markers for Germline Transformation 2. Inducible / Repressible Systems for Transgene Expression 3. Transposable Elements for Insect Transformation 4. Sex, Tissue and Stage--(c)\specific Transgene Expression 5. Docking Systems 6. Gene Drive Systems 7. Site Specific Recombination Alternative Transgenic Approaches to Modifying Insect Phenotypes 8. Paratransgenesis of Tsetse 9. Paratransgenesis of Glassy Winged Sharpshooter 10. Paratransgenesis of kissing bugs 11. Asaia Paratransgenesis of Mosquitoes 12. Transgenic densovirus and viral paratransgenesis Applications of Transgenic Insect 13. Sexual Sterilization of Mosquitoes 14. Understanding Development Using Tribolium Transgenesis 15. Pharma and modified silk: silkworm applications 16. Fruit Fly Transgenesis and Applications 17. Understanding Diseases Relevant to Public Health Using Anti C pathogen Effectors 18. Conditional Dominant Lethals C RIDL 19. Modification of Sex Ratio 20. Transformation (beside fruit flies) Modeling Effectiveness of Transgenic Technologies 21. RIDL: Release of Insects Carrying a Dominant Lethal 22. Homing Endonuclease Genes 23. Driving Anti--(c)\pathogen Genes 24. Medea, Inverse Medea & Semale Considerations For the Release Of Transgenic Insects 25. Public Acceptance Of Transgenic Insect Applications 26. Assessing Risk of Transgenic Insects 27. Economics of Transgenic Insects for Field Release 28. Regulation of Transgenic Insects