In Vitro Toxicity Testing Protocols - Atterwill, Christopher K.

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Sommaire:
Alternative Method of Assessing Toxicity.- Alternative Method of Assessing Toxicity.- Target Organ Toxicity.- LLC-RK1 Cell Screening Test for Nephrotoxicity.- Preparation and Use of Cultured Astrocytes for Assay of Gliotoxicity.- Human Thyroid Culture.- Thyroid Follicular Cells in Monolayer Culture.- Dust Toxicity in Rat Alveolar Macrophage Cultures.- Hepatoma Cell Cultures as In Vitro Models for Hepatotoxicity.- Cytotoxicity, DNA Fragmentation, and DNA Repair Synthesis in Primary Human Hepatocytes.- Model Cavity Method.- Human Esophageal Culture.- The Application of In Vitro Models of Anterior Pituitary Function in Toxicity Testing.- The Application of In Vitro Models of Hypothalamic Function in Toxicity Testing.- General and Topical Toxicity.- The FRAME Cytotoxicity Test (Kenacid Blue).- Allium Test.- Measurement of Cell Membrane Toxicity by Means of 2-Deoxy-D-Glucose.- MTT Assays.- V79 Cytotoxicity Test for Membrane Damage.- SIRC Cytotoxicity Test.- Rabbit Articular Chondrocyte Functional Toxicity Test.- Balb/c 3T3 Cytotoxicity Test.- The Pollen Tube Growth Test.- Irritancy Testing.- HET-CAM Test.- The Use of the Bovine Isolated Cornea as a Possible In Vitro Test for Occular Irritancy.- Cytotoxicity in an Anchorage-Independent Fibroblast Cell Line Measured by a Combination of Fluorescent Dyes.- Cell Culture Phototoxicity Test.- Immunotoxicity.- The Murine Local Lymph Node Assay.- Polymorphonuclear Leukocyte Locomotion.- Immune Function Assays.- Carcinogenesis.- The DNA Alkaline Unwinding Genotoxicity Test.- Measurement of Unscheduled DNA Synthesis In Vitro Using Primary Rat Hepatocyte Cultures.- Gene Mutation Assays in Mammalian Cells.- Measurement of Chromosome Aberrations In Vitro Using Human Peripheral Blood Lymphocytes.- Mutation Assays in Bacteria.- Submammalianand Subvertebrate Models.- Chick Embryotoxicity Screening Test (CHEST I and II).- Frog Embryo Teratogenesis Assay.- The Drosophila melanogaster Assay.- The Hydra attenuata Assay.