Central Nervous System Diseases -

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Sommaire:
1 ? The Cholinergic Hypothesis a Generation Later: Perspectives Gained on the Use and Integration of Animal Models.- 2 ? Patterns of Cognitive Decline in the Aged Rhesus Monkey.- 3 ? Cholinergic Lesions as a Model of Alzheimer's Disease: Effects of Nerve Growth Factor.- 4 ? The Immunolesioned Animal as a Model of Transmitter Dysfunction.- 5 ? An Intracerebral Tumor Necrosis Factor-? Infusion Model for Inflammation in Alzheimer's Disease.- 6 ? The Senescence-Accelerated Mouse as a Possible Animal Model of Senile Dementia.- 7 ? Transgenic Mice Overexpressing Presenilin cDNAs: Phenotype and Utility in the Modeling of Alzheimer's Disease.- 8 ? Intervention Strategies for Degeneration of Dopamine Neurons in Parkinsonism: Optimizing Behavioral Assessment of Outcome.- 9 ? Development of Behavioral Outcome Measures for Preclinical Parkinson's Research.- 10 ? Behavioral Assessment in the Unilateral Dopamine-Depleted Marmoset.- 11 ? Molecules for Neuroprotection and Regeneration in Animal Models of Parkinson's Disease.- 12 ? Antisense Knockdown of Dopamine Receptors.- 13 ? Is Trophic Factor Gene Disruption a Knockout Model for Parkinson's Disease?.- 14 ? Operant Analysis of Striatal Dysfunction.- 15 ? Intrastriatal Injections of Quinolinic Acid as a Model for Developing Neuroprotective Strategies in Huntington's Disease.- 16 ? Systemic Administration of 3-Nitropropionic Acid: A New Model of Huntington's Disease in Rat.- 17 ? Replicating Huntington Disease's Phenotype in Nonhuman Primates.- 18 ? Transgenic Mouse Models of Huntington's Disease.- 19 ? Rigid Indentation Models of Traumatic Brain Injury in the Rat.- 20 ? Rodent Ischemia Models of Embolism and Ligation of the Middle Cerebral Artery: Clinical Relevanceto Treatment Strategies of Stroke.- 21 ? A Primate Model of Hypertensive Cerebrovascular Disease.- 22 ? Nictotinic Therapeutics for Tourette Syndrome and Other Neuropsychiatric Disorders: From Laboratory to Clinic.- 23 ? Neural Grafting for Parkinson's and Huntington's Disease.- 24 ? Future Prospects of Gene Therapy for Treating CNS Diseases.