Multiple Sclerosis, Mad Cow Disease and Acinetobacter - Ebringer, Alan

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Résumé :
The aim of this book is to publicise and bring to a wider audience the concept that the cause of two neurological diseases, namely multiple sclerosis (MS) and ?mad cow disease? also known as ?bovine spongiform encephalopathy? are related through exposure to a common microbe Acinetobacter which is found in human sinuses, on skin and in the soil. An infection is the cause of a neurological disease in man and in animals. Elevated levels of antibodies to Acinetobacter have been found in multiple sclerosis patients as well as in ruminants who have been described as suffering from ?mad cow disease? following exposure to contaminated feed supplements. The overall objective and scope of this book is to inform the audience, the reader, that multiple sclerosis may be linked to a microbe Acinetobacter which carries molecular structures resembling myelin, the outer sheath covering of neurons.

Biographie:
Professor Alan Ebringer, Department of Rheumatology, The Middlesex Hospital UCH School of Medicine and Infection & Immunity Group, Division of Life Sciences, Kings College, London, UK.

Sommaire:

1. Multiple Sclerosis as a Scientific Problem.- 2. History of the Attempts to find the Origin of Multiple Sclerosis.- 3. The Problem of Bovine Spongiform Encephalopathy also known as Mad Cow Disease in the United Kingdom.- 4. Experimental Allergic Encephalomyelitis as a Model of Multiple Sclerosis.- 5. Bovine Spongiform Encephalopathy: Comparison between the Prion Hypothesis in EAE and BSE Point to Acinetobacter Bacteria.- 6. Molecular Sequences in EAE and BSE Point to Acinetobacter Bacteria.- 7. Autoantibodies to Brain Components and Antibodies to Acinetobacter are Present in Bovine Spongiform Encephalopathy.- 8. Antibodies to Acinetobacter Bacteria but not to other Microbes are Present in Animals with Bovine Spongiform Encephalopathy.- 9. An Ante-Mortem Test for Bovine Spongiform Encephalopathy involving Myelin-Acinetobacter-Neurofilaments (MAN) Tested in 12 Strains of Acinetobacter Bacteria.- 10. Antibodies to Acinetobacter and Pseudomonas Bacteria in Bovine Spongiform Encephalopathy.- 11. Antibodies to Acinetobacter and Pseudomonas Bacteria in Multiple Sclerosis Patients.- 12. Antibodies to Acinetobacter Peptide Sequences Resembling Myelin and Neurofilaments in Multiple Sclerosis Patients.- 13. The Myelin Acinetobacter Neurofilament Index in an Attempt to Diagnose Multiple Sclerosis.- 14. Antibodies to Short Synthetic Acinetobacter and Pseudomonas Peptide Sequences Resembling Myelin and Neurofilaments in Multiple Sclerosis Patients.- 15. Antibodies to Acinetobacter and Myelin in Multiple Sclerosis and Creutzfeldt-Jakob Disease Patients.- 16. Creutzfeldt-Jakob Disease and its Variants.- 17. Sinusitis in Multiple Sclerosis and Acinetobacter.- 18. The Theory that Multiple Sclerosis, CJD and BSE are Caused by Acinetobacter.- 19. The Scientific Method of Sir Karl Popper.- 20. Multiple Sclerosis and Popper Sequences.