Crystal Engineering - Williams, Jeffrey H

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Résumé :
There are more than 20 million chemicals in the literature, with new materials being synthesized each week. Most of these molecules are stable, and the 3-dimensional arrangement of the atoms in the molecules, in the various solids may be determined by routine x-ray crystallography. When this is done, it is found that this vast range of molecules, with varying sizes and shapes can be accommodated by only a handful of solid structures. This limited number of architectures for the packing of molecules of all shapes and sizes, to maximize attractive intermolecular forces and minimizing repulsive intermolecular forces, allows us to develop simple models of what holds the molecules together in the solid. In this volume we look at the origin of the molecular architecture of crystals; a topic that is becoming increasingly important and is often termed, crystal engineering. Such studies are a means of predicting crystal structures, and of designing crystals with particular properties by manipulating the structure and interaction of large molecules. That is, creating new crystal architectures with desired physical characteristics in which the molecules pack together in particular architectures; a subject of particular interest to the pharmaceutical industry.

Biographie:
particularly, neutron scattering. During this research career, he published more than sixty technical papers and invited review articles in the peer-reviewed literature. However, after much thought he left research in 1992 and moved to the world of science publishing and the communication of science by becoming the European editor for the physical sciences for the AAAS's Science.

Subsequently, he was Assistant Executive Secretary of the International Union of Pure and Applied Chemistry...

Sommaire:

Jeffrey Huw Williams was born in Swansea, Wales, on 13 April 1956, and gained a PhD in chemical physics from Cambridge University in 1981. Subsequently, his career as a research scientist was in the physical sciences. First, as a research scientist in the universities of Cambridge, Oxford, Harvard and Illinois, and subsequently as an experimental physicist at the Institute Laue-Langevin, Grenoble, which still remains one of the world's leading centres for research involving neutrons...