Molecular Basis for Mitochondrial Signaling -

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Sommaire:
Mitochondrial Calcium Signaling.- Systems approaches to mitochondrial calcium signaling.- The mitochondrial Calcium Uniporter: Molecular Composition And Physiological Role.- Molecular Mechanisms of Mitochondrial Ca2+ Uptake.- Ca2+ uniporter and male fertility.- The Mitochondrial Permeability Transition pore: Finally Structure Meets Function.- ATP synthase forms the Mitochondrial Permeability Transition Pore.- C-subunit ring of the ATP synthase is the mitochondrial permeability transition pore.- Mitochondrial Outer Membrane Transport Systems: Structure, Function, and Physiological Implications.- VDAC and tubulin in regulation of mitochondrial metabolism.- Warburg revised: regulation of mitochondrial metabolism by VDAC in cancer cells.- VDAC isoforms in mammals.- Plant VDAC: function, structure, computational studies.- VDAC 1, 2 structure and structure-guided simulations of ATP translocation and VDAC gating.- MD simulations of VDAC selectivity and gating.- TSPO interacts with VDAC1 and triggers a ROS mediated inhibition of mitochondrial quality control.- VDAC/Hexokinase complex as a generator of the mitochondrial outer membrane potential.- TOM complex, Tom40 - protein translocator complex of the mitochondrial outer membrane.- Mitochondria And Cellular Signaling Network.- Mitochondrial Interactosome: mitochondria and cytoskeleton; cardiac mitochondria.- Mitochondrial respiration and ROS.- Diversity of Mitochondria Outer Membrane Permeabilization (MOMP) Pathways: Structure and Mechanism.- Molecular identity of mitochondrial apoptosis-induced channels (MAC).- Ceramide channels in the mitochondrial outer membrane.- Bax regulates ceramide synthase and ceramide-induced apoptosis.- Biophysical changes in bilayer properties following Bax insertion into a membrane.- A new view of the lethal apoptotic pore (Bax).- Other Mitochondrial Channels.- K(ATP) channels in the inner membrane.