Biomedical Technology -

. .

Résumé :
During the last years computational methods lead to new approaches that can be applied within medical practice. Based on the tremendous advances in medical imaging and high-performance computing, virtual testing is able to help in medical decision processes or implant designs. Current challenges in medicine and engineering are related to the application of computational methods to clinical medicine and the study of biological systems at different scales. Additionally manufacturers will be able to use computational tools and methods to predict the performance of their medical devices in virtual patients. The physical and animal testing procedures could be reduced by virtual prototyping of medical devices. Here simulations can enhance the performance of alternate device designs for a range of virtual patients. This will lead to a refinement of designs and to safer products. This book summarizes different aspects of approaches to enhance function, production, initialization and complications of different types of implants and related topics.

Sommaire:
RVE procedure for estimating the elastic properties of inhomogeneous microstructures such as bone tissue.- A gradient-enhanced continuum damage model for residually stressed fibre-reinforced materials at finite strains.- A mechanically stimulated fracture healing model using a finite element framework.- The customized artificial hip cup: design and manufacturing of an innovative prosthesis.- On the role of phase change in modelling drug-eluting stents.- Development of magnesium alloy scaffolds to support biological myocardial grafts.- Finite element analysis of transcatheter aortic valve implantation in the presence of aortic leaflet calcifications.- Repair of mitral valve prolapse through ePTFE neochordae: a finite element approach from CMR.- An extended computational framework to study arterial vasomotion and its links to vascular disease.- Development of a model of the electrically stimulated cochlea.- Implant related infections.- Animal test models for implant associated inflammation and infections.