Protein Folding Protocols -

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Résumé :
Covering experiment and theory, bioinformatics approaches, and state-of-the-art simulation protocols for better sampling of the conformational space, this volume describes a broad range of techniques to study, predict, and analyze the protein folding process. Protein Folding Protocols also provides sample approaches toward the prediction of protein structure starting from the amino acid sequence, in the absence of overall homologous sequences.

Sommaire:
Infrared Temperature-Jump Study of the Folding Dynamics of a-Helices and b-Hairpins Feng Gai, Deguo Du, and Yao Xu The Use of High-Pressure Nuclear Magnetic Resonance to Study Protein Folding Michael W. Lassalle and Kazuyuki Akasaka Characterization of Denatured Proteins Using Residual Dipolar Couplings Erika B. Gebel and David Shortle Characterizing Residual Structure in Disordered Protein States Using Nuclear Magnetic Resonance David Eliezer Population and Structure Determination of Hidden Folding, Intermediates by Native-State Hydrogen Exchange-Directed Protein Engineering and Nuclear Magnetic Resonance Yawen Bai, Hanqiao Feng, and Zheng Zhou Characterizing Protein Folding Transition States Using Y-Analysis Adarsh D. Pandit, Bryan A. Krantz, Robin S. Dothager, and Tobin R. Sosnick Advances in the Analysis of Conformational Transitions in Peptides Using Differential Scanning Calorimetry Werner W. Streicher and George I. Makhatadze Application of Single Molecule F?rster Resonance Energy Transfer to Protein Folding Benjamin Schuler Single Molecule Studies of Protein Folding Using Atomic Force Microscopy Sean P. Ng, Lucy G. Randles, and Jane Clarke Using Triplet-Triplet Energy Transfer to Measure Conformational Dynamics in Polypeptide Chains Beat Fierz, Karin Joder, Florian Krieger, and Thomas Kiefhaber A Hierarchical Protein Folding Scheme Based on the Building Block Folding Model Nurit Haspel, Gilad Wainreb, Yuval Inbar, Hui-Hsu (Gavin) Tsai, Chung-Jung Tsai, Haim J. Wolfson, and Ruth Nussinov Replica Exchange Molecular Dynamics Method for Protein Folding Simulation Ruhong Zhou Estimation of Folding Probabilities and F Values From Molecular Dynamics Simulations of Reversible Peptide Folding Francesco Rao, Giovanni Settanni, and Amedeo Caflisch PackingRegularities in Biological Structures Relate to Their Dynamics Robert L. Jernigan and Andrzej Kloczkowski Intermediates and Transition States in Protein Folding D. Thirumalai and Dmitri K. Klimov Thinking the Impossible: How to Solve the Protein Folding Problem With and Without Homologous Structures and Morem Rita Casadio, Piero Fariselli, Pier Luigi Martelli, and Gianluca Tasco Index