Renal Physiology - Bruce A. Stanton

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Résumé :

INTRODUCTION

CHAPTER 1

PHYSIOLOGY OF BODY FLUIDS

Objectives

Concept of Steady-State Balance

Physicochemical Properties of Electrolyte Solutions

Molarity and Equivalence

Osmosis and Osmotic Pressure

Osmolarity and Osmolality

Tonicity

Oncotic Pressure

Specific Gravity

Volumes of Body Fluid Compartments

Composition of Body Fluid Compartments

Fluid Exchange between Body Fluid Compartments

Capillary Fluid Exchange

Cellular Fluid Exchange

Summary

Key Words and Concepts

Self-Study Problems

Objectives

Structure of the Kidneys

Gross Anatomy

Ultrastructure of the Nephron

Ultrastructure of the Glomerulus

Ultrastructure of the Juxtaglomerular Apparatus

Innervation of the Kidneys

Summary

Key Words and Concepts

Self-Study Problems

Objectives

Renal Clearance

Glomerular Filtration Rate

Glomerular Filtration

Determinants of Ultrafiltrate Composition

Dynamics of Ultrafiltration

Renal Blood Flow

Regulation of Renal Blood Flow and Glomerular Filtration Rate

Sympathetic Nerves

Angiotensin II

Prostaglandins

Nitric Oxide

Endothelin

Bradykinin

Adenosine

Natriuretic Peptides

Adenosine Triphosphate

Glucocorticoids

Histamine

Dopamine

Summary

Key Words and Concepts

Self-Study Problems

Objectives

General Principles of Membrane Transport

General Principles of Transepithelial Solute and Water Transport

NaCl, Solute, and Water Reabsorption Along the Nephron

Regulation of NaCl and Water Reabsorption

Summary

Key Words and Concepts

Self-Study Problems

Objectives

Arginine Vasopressin

Osmotic Control of Arginine Vasopressin Secretion

Hemodynamic Control of Arginine Vasopressin Secretion

Arginine Vasopressin Actions on the Kidneys

Thirst

Renal Mechanisms for Dilution and Concentration of the Urine

Medullary Interstitium

Vasa Recta Function

Assessment of Renal Diluting and Concentrating Ability

Summary

Key Words and Concepts

Self-Study Problems

Objectives

Whole-Body Na+ Balance

Concept of Effective Circulating Volume

Volume-Sensing Systems

Volume Sensors in the Low-Pressure Cardiopulmonary Circuit

Volume Sensors in the High-Pressure Arterial Circuit

Volume Sensor Signals

Renal Sympathetic Nerves

Renin-Angiotensin-Aldosterone System

Natriuretic Peptides

Arginine Vasopressin

Control of Renal NaCl Excretion During Euvolemia

Mechanisms for Maintaining Constant Na+ Delivery to the Distal Tubule in Euvolemia

Regulation of Distal Tubule and Collecting Duct Na+ Reabsorption in Euvolemia

Control of Na+ Excretion with Volume Expansion

Control of Na+ Excretion with Volume Contraction

Edema

Alterations in Starling Forces

Capillary Hydrostatic Pressure (Pc)

Plasma Oncotic Pressure (?c)

Lymphatic Obstruction

Capi...

Biographie:
Bruce Koeppen, founding dean of the Frank H. Netter MD School of Medicine at Quinnipiac, recently received two prestigious awards: honored by the Patient is U Foundation - a nonprofit that aims to encourage human communication in health care and support both patients and providers and the (LCME) Liaison Committee on Medical Education's 2019 Distinguished Service Award.

Sommaire:
Bruce Koeppen, founding dean of the Frank H. Netter MD School of Medicine at Quinnipiac, recently received two prestigious awards: honored by the Patient is U Foundation - a nonprofit that aims to encourage human communication in health care and support both patients and providers and the (LCME) Liaison Committee on Medical Education's 2019 Distinguished Service Award....