Veterinary Epidemiology - Thrusfield, Michael School of Veterinary Studies

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Résumé :
Eine umfassende Einf?hrung zur Rolle der Epidemiologie in der Veterin?rmedizin.

Die vollst?ndig ?berarbeitete und erweiterte Ausgabe von Veterinary Epidemiology f?hrt den Leser in das Fachgebiet der Veterin?repidemiologie ein. Diese neue Auflage bietet auch neue Kapitel zur Konzeption von Beobachtungsstudien, Validit?t von epidemiologischen Studien, zu systematischen Pr?fungen und zu statistischen Modellen.

Die aktualisierte Auflage beginnt mit einem historischen Blick auf die Entwicklung der Veterin?rmedizin. Im Anschluss wird die Fachrichtung Epidemiologie umfassend beleuchtet. Kapitel befassen sich mit den Aspekten Kausalit?t, Auftreten von Krankheiten, Bestimmungsfaktoren, Krankheitsmustern, Krankheits?kologie u.v.m.

Veterinary Epidemiology, 4. Auflage:
- Alle Kapitel wurden aktualisiert. Entstanden ist ein modernes Referenzwerk zum Thema Veterin?repidemiologie.
- Enth?lt neue Kapitel, die f?r die Entwicklung des Fachgebiets ma?geblich sind.
- Bietet Beispiele zu Haustieren, Nutztieren und V?geln sowie zu Krankheiten bei Wassertieren.
- Richtet den Fokus auf Prinzipien und Konzepte der Epidemiologie, der ?berwachung, der Validierung und Leistungsf?higkeit diagnostischer Tests.
- Begleitende Website mit Multiple-Choice-Fragen.

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Biographie:

MICHAEL THRUSFIELD is Professor of Veterinary Epidemiology at the Royal (Dick) School of Veterinary Studies in the University of Edinburgh in Edinburgh, UK.

ROBERT CHRISTLEY is Professor of Epidemiology and One Health at the Institute of Infection and Global Health and the Institute of Veterinary Science in the University of Liverpool in Liverpool, UK....

Sommaire:

Contributors xviii

From the preface to the first edition xix

From the preface to the second edition xx

From the preface to the third edition xxi

Preface to the fourth edition xxii

About the companion website xxiv

1 The development of veterinary medicine 1
Michael Thrusfield

Historical perspective 1

Domestication of animals and early methods of healing 1

Changing concepts of the cause of disease 2

Impetus for change 5

Quantification in medicine 10

Contemporary veterinary medicine 12

Current perspectives 12

The fifth period 19

Recent trends 20

Further reading 25

2 The scope of epidemiology 28
Michael Thrusfield

Definition of epidemiology 28

The uses of epidemiology 29

Types of epidemiological investigation 32

Epidemiological subdisciplines 33

Components of epidemiology 35

Qualitative investigations 35

Quantitative investigations 36

Epidemiology's locale 39

The interplay between epidemiology and other sciences 39

The relationship between epidemiology and other diagnostic disciplines 40

Epidemiology within the veterinary profession 40

Further reading 41

3 Causality 42
Michael Thrusfield

Philosophical background 42

Causal inference 43

Methods of acceptance of hypotheses 44

Koch's postulates 45

Evans' rules 45

Variables 46

Types of association 46

Non-statistical association 46

Statistical association 46

Confounding 49

Causal models 50

Formulating a causal hypothesis 53

Methods of deriving a hypothesis 53

Principles for establishing cause: Hill's criteria 55

Further reading 56

4 Describing disease occurrence 58
Michael Thrusfield

Some basic terms 58

Basic concepts of disease quantification 61

The structure of animal populations 62

Contiguous populations 62

Separated populations 65

Measures of disease occurrence 67

Prevalence 67

Incidence 67

The relationship between prevalence and incidence rate 70

Application of prevalence and incidence values 72

Mortality 72

Survival 73

Example of calculation of prevalence, incidence, mortality, case fatality and survival 75

Ratios, proportions and rates 76

Mapping 80

Geographic base maps 80

Further reading 84

5 Determinants of disease 86
Michael Thrusfield

Classification of determinants 86

Host determinants 89

Genotype 89

Age 90

Sex 91

Species and breed 92

Behaviour 93

Other host determinants 93

Agent determinants 94

Virulence and pathogenicity 94

Gradient of infection 97

Outcome of infection 98

Microbial colonization of hosts 100

Environmental determinants 101

Location 101

Climate 101

Husbandry 104

Stress 105

Interaction 106

Biological interaction 108

Statistical interaction 109

The cause of cancer 110

Further reading 112

6 The transmission and maintenance of infection 115
Michael Thrusfield

Horizontal transmission 115

Types of host and vector 115

Factors associated with the spread of infection 118

Routes of infection 121

Methods of transmission 123

Long-distance transmission of infection 125

Vertical transmission 129

Types and methods of vertical transmission 129

Immunological status and vertical transmission 129