Cancer Therapy -

Résumé :
In more than 20 contributions new trends in cancer therapy are reviewed and critically discussed by highly competent authors. Their contributions are based on an international symposium and cover all major fields of clinical oncology. Special emphasis is given to surgical oncology (including photodynamic laser therapy and radiosurgery), radiation oncology, hyperthermia, new antineoplastic agents, enzyme-pattern-targeted chemotherapy, drug resistance, biological response modifiers, bone marrow transplantation, antibody guided therapy, induction of cell differentiation in transformed cells, and the individualization of tumor therapy. The stimulating discussion at the end of each section covering these topics will particulary benefit the clinical oncologist and all researchers devoted to the improvement of cancer therapy.

Sommaire:
Session 1 Surgery.- Advances in Surgical Oncology.- Photodynamic Laser Therapy of Photosensitized Tumors.- Radiosurgery with a Linear Accelerator: Method, Indications and Preliminary Results.- Summary of Discussion: Session 1.- Session 2 Radiation.- New Trends in Radiation Therapy: Fast Neutrons and New Particles.- Altered Fractionation in Radiotherapy.- New Trends in Computer-Assisted Radiotherap with Conventional Radiation.- Intraoperative Radiation Therapy for Glioblastoma - Indications and Treatment Results.- Summary of Discussion: Session 2.- Session 3 Hyperthermia.- Hyperthermia in Tumor Treatment.- Regional Hyperthermia and Systemic Chemotherapy.- Summary of Discussion: Session 3.- Session 4 Chemotherapy.- New Trends in Chemotherapy of Tumors.- New Antineoplastic Agents.- Enzyme-Pattern-Targeted Chemotherapy.- Nuclear Components and Plasma Membrane as Targets of Chemotherapeutic Agents.- Drug Resistant Cells as Targets for Chemotherapeutic Agents.- Summary of Discussion: Session 4.- Session 5 Biological Response.- Biological Response Modifiers: Mechanisms of Action.- Biological Response Modifiers: Clinical Aspects.- Predictive Assays for the Individualization of Tumor Therapy.- Molecular Genetic Changes as Indicators of Therapeutic Effectiveness.- Summary of Discussion: Session 5.- Session 6 Bone Marrow Transplantation.- Allogeneic Marrow Transplantation in Acute Leukemia and Chronic Myelogenous Leukemia - Johns Hopkins Experience.- Autologous Bone Marrow Transplantation.- Summary of Discussion: Session 6.- Session 7 Antibody Guided Therapy.- Predictive Pharmacology of Monoclonal Antibodies.- A New Approach in the Treatment of Advanced Ovarian Cancer and Brain Glioma Using Radiolabelled Monoclonal Antibodies.- Ricin A Chain - Monoclonal Antibody 791T/36 Immunotoxin for Treatment of Colorectal and Ovarian Cancer.- Experimental Approaches to Tumor Therapy with Monoclonal Antibodies.- Summary of Discussion: Session 7.- Session 8 Cell Differentiation and Growth.- Induced Differentiation of Transformed Cells by Polar Compounds: From Molecular Studies to Clinical Trials.- Hematopoietic Cytokines in Cancer Therapy: Concepts and First Clinical Observations.- Summary of Discussion: Session 8.