Neuron-Glia Interrelations During Phylogeny - Roots, Betty I.

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Résumé :
Leading international authorities report on their in vivo studies of neuron-glia interactions in animals with simple nervous systems (insects, fish, amphibians, and reptiles). Their work amounts to an in-depth account of many of the principal functions of glial cells: myelination, regulation of ionic environment, neurotransmitter compartmentation and neurotransmitter receptors, blood-brain barrier, regeneration, and aging. Part I examines the origin and role of glial cells during development across the phylogenetic spectrum, including the evolution of their particular functions. Part II discusses the physiological and metabolic interactions between neurons and glia, again across phylogenetic groups. Neuron-Glia Interrelations During Phylogeny illuminates the evolution of the nervous system and expands our knowledge of the mechanisms involved in regeneration and central nervous system repair. It constitutes a virtual encyclopedia of up-to-date findings concerning the significant roles played by glial cells in neuronal development and function.

Sommaire:
I. Physiological Glia-Neuron Interaction in Phylogeny.- Neuron-Glia Interactions in the Human Fetal Brain.- Glial Cells Play a Key Role in the Construction of Insect Olfactory Glomeruli.- Insect Glial Cells and Their Relationships with Neurons.- Metabolite Exchanges and Signal Trafficking Between Glial Cells and Neurons in the Insect Retina.- Learning from the Axon-Schwann Cell Relationships of the Giant Nerve Fiber of the Squid.- Glutamate-Mediated Neuron-Glia Signaling in Invertebrates and Vertebrates.- Metabolic Interactions Between Neurons and Glial Cells in Leech and Snail Ganglia.- Functional Role of Ion Transporters and Neurotransmitter Receptors in Glia.- II. Plasticity and Regeneration of CNS in Phylogeny.- Regeneration in the Mammalian CNS: New and Old Views.- Cells at the Boundary: The Insect Blood-Brain Barrier and Its Role in Neural Repair.- Neuron-Glia Interrelations During 3-Acetylpyridine-Induced Degeneration and Regeneration in the Adult Lizard Brain.- The Role of Extracellular Matrix Molecules, Glial Cells, and Microglia in Regeneration of the Leech CNS.- The Organization of Astrocytes in the Goldfish Visual System.- Repair by Schwann Cells in the Regenerating Goldfish Visual Pathway: Evidence of Regional Specificity.- Intermediate Filaments: A Molecular Link to Nerve Development and Regeneration in the Goldfish Visual Pathway.- Neuroglia in Adult Amphibians.- Plasticity of Astrocytes in Culture: Comparison of Astrocytes Derived from Chick Embryonic Brain and Aged Mouse Brain.- Glia-Neuronal and Glia-Vascular Interrelations in Blood-Brain Barrier Formation and Axon Regeneration in Vertebrates.