Hemoglobin Function in Vertebrates -

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Résumé :
This volume comprises selected contributions by internationally renowned researchers and represents the state-of-the-art in the field of hemoglobin function in vertebrates living in extreme and temperate environments. The topics have been covered from several viewpoints, including protein chemistry, molecular biology, and evolution. All the contributions chosen for publication focus on phenotypic and genetic adaptations to changing environmental conditions and on gene expression and regulation. The book provides the reader with an update in this field, which is presently enjoying a true renaissance following developments in recent years of powerful methodologies such as site-directed mutagenesis and discoveries of new roles, for example, as oxygen sensors and in nitric oxide metabolism.

Sommaire:
Molecular Aspects of Temperature Adaptation.- Adaptations for Oxygen Transport: Lessons from Fish Hemoglobins.- Recent Evolution of the Hemoglobinless Condition of the Antarctic Icefishes.- Oxygen-Transport System and Mode of Life in Antarctic Fish.- Functional Properties of the Cathodic Hemoglobin Component from Two Species of Anguilliformes.- Oxygen Transport in Diving Vertebrates.- Oxygen Transport and Diving Behaviour: The Haemoglobin from Dolphin Tursiops truncatus.- Molecular Modelling Analysis of the Haemoglobins of the Antarctic Bird Catharacta maccormicki: the Hypothesis of a Second Phosphate Binding Site.- Transport of Oxygen during Hibernation: the Hemoglobin of Dryomys nitedula.- The Hemoglobin Polymorphism in Sardinian Goats: Nucleotide Sequence and Frequency of ?A, ?D, ?D-Malta, and ?E Globin Genes.- The Organization of the 13-Globin Gene Cluster and the Nucleotide Sequence of the ?-Globin Gene of Cyprus Mouflon (Ovis gmelini ophion).