Machine Learning in Medicine - Zwinderman, Aeilko H.

Professor Zwinderman is one of the Principle Investigators of the Academic Medical Center Amsterdam, and his research is concerned with developing statistical methods for new research designs in biomedical science, particularly integrating omics data, like genomics, proteomics, metabolomics, and analysis tools based on parallel computing and the use of cluster computers and grid computing.

Professor Cleophas is a member of the Academic Committee of the European College of Pharmaceutical Medicine, that provides, on behalf of 22 European Universities, the Master-ship trainings Pharmaceutical Medicine and Medicines Development.

From their expertise theyshould be able to make adequate selections of modern methods for clinical data analysis for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 18 years, and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.

The authors as professors and teachers in statistics at universities in The Netherlands and France for the most part of their lives, are concerned, that their students find regression-analyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regression-analysis, and they do hope that the current production Regression Analysis for Starters and 2nd Levelers will be a helpful companion for the purpose.

Statistics applied to clinical studies 5th edition, 2012, ...

Sommaire:
Preface1? ??????????Introduction to Machine Learning Part Three????????????? ????????????????????? ???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????2? ??????????Evolutionary Operations??? ????? ?????????????????????????????????????3???????????? Multiple Treatments???????????????????????????????????????????????????????????????????????????????????????? 4???????????? Multiple Endpoints?????????????????????????????????????????????????????????????????????????????????????????? 5???????????? Optimal Binning???????????????? ?????????????????????????????????????????????????????????????? 6???????????? Exact P-Values????????????????????????????????????????????????????????????????????????????????????????????????? 7???????????? Probit Regression??????????????????????????????? ?????????????????????????????????????????????????????????????? 8???????????? Over-dispersion?????????????????? ????????????????????????????????????????????????????????????????????????????? 9???????????? Random Effects???????????????? ????????????????????????????????????????????????????????????????????????????? 10?????????? Weighted Least Squares???????? ?????????????????????????????????????????????????????????????????????????? 11?????????? Multiple Response Sets???? ????????????????????????????????????????????????????????????????????????????? 12?????????? Complex Samples????????????? ?????????????????????????????????????????????????????????????? ??????????????? 13?????????? Runs Tests?????????????????????????? ????????????????????????????????????????????????????????????????????????????? 14?????????? Decision Trees???????????????????????????????????? ?????????????????????????????????????????????????????????????? 15?????????? Spectral Plots?????????????????????? ????????????????????????????????????????????????????????????????????????????? 16?????????? Newton's Methods??????????? ???????????????????????????????????????????????????????????????????????????????? 17?????????? Stochastic Processes, Stationary Markov Chains ???????????????????????????????????? 18?????????? Stochastic Processes, Absorbing Markov Chains ????????????????????????????????????? 19?????????? Conjoint Models ????????????????????????????????????????????????????????????????????????????? 20?????????? Machine Learning and Unsolved Questions??????????????????????????????? Index ???