Deep Brain Stimulation Programming - Montgomery Jr, Erwin B

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Résumé :

• Table of Contents
• Preface to the Second Edition
• Preface to the First Edition
• Abbreviations
• Chapter 1. Introduction
• The Fundamentals Still Pertain
• Principles of Effective and Efficient Programming
• The Basis of DBS Effects
• Chapter 2. Principles of DBS Electronics
• Electricity
• Electronics
• Note Regarding Impedances
• Chapter 3. Principles of Electrophysiology
• Therapeutic Mechanisms versus Delivery of Therapy
• The Neuron
• Neuronal Electronics
• Voltage Gated Ionic Conductance Channels and Action Potentials
• Downstream Secondary Issues
• Chapter 4. Controlling the Flow of Electrical Charges
• Orientation of the Lines of Electrical Force
• Orthodromic and Antidromic Conduction of Action Potentials
• Axon Diameter
• Electrode Configurations
• Current Intensity in Monopolar and Bipolar Electrode Configurations
• Segmented DBS Leads
• Chapter 5. DBS Safety
• The Range of Safety Concerns
• Injury Secondary to Electricity
• Medical Complications
• Adverse Effects Related to Activation of Neural Networks
• The Potential Psychosocial Consequences of DBS
• Chapter 6. Nervous System Responses to DBS
• Knowledge of Nervous System Responses versus Knowledge of Therapeutic Mechanisms
• Effects Mediated by Voltage-Gated Ionic Conductance Channels in the Neuronal Membrane
• Post-Hyperpolarization Rebound Excitation, Depolarization Blockade, and Neurotransmitter Exhaustion
• Dissociation of Effects on Action Potential Initiating Segment, Dendrites, and Cell Bodies
• Network Effects of DBS
• Critically Important Caveats Concerning Interpretation of Nervous System Responses to DBS
• Reentry Propagations and Resonance
• Synchronization Among Neurons
• Interactions Between DBS Pulse in Intrinsic Neuronal Mechanisms
• Effects on Behaviorally Related Intrinsic Neuronal Dynamic
• Temporal Evolution of Nervous System Responses
• Chapter 7. DBS Effects on Motor Control
• Orchestration of Motor Unit Activities
• Orchestration of Motor Unit Recruitment and De-Recruitment over Different Time Scales
• Lessons to be Learned
• Chapter 8. Pathophysiological Mechanisms
• The Globus Pallidus Interna Rate Theory
• Excessively High Beta Oscillations
• Excessive Synchronization of Neuronal Activities
• Excessive Bursting
• The Systems Oscillators Theory
• Chapter 9. Approaches to Programming
• Battery Life
• DBS Contact Nomenclature
• Prior to DBS Programming
• When to Program DBS
• Conceptual Approaches
• The Growing Importance of Monopolar Surveys
• Detection of a Response is Critical
• Programming for Optimal Benefit in the Absence of Adverse Effects
• Programming to Prevent Adverse Effects
• Exiting the DBS Programming Session
• Chapter 10. Clinical Assessments
• Clinical Assessments by Disease
• Clinical Assessment of Corticospinal and Corticobulbar Stimulation
• Clinical Assessment of Speech, Language and Swallowing
• Hints to Clinical Evaluations
• Chapter 11. Approach to Subthalamic Nucleus
• Regional Anatomy of the Subthalamic Nucleus
• Adverse Effects Created by the Position of the DBS Lead Relative to the STN
• Approach to STN DBS for Parkinson's Disease
• Chapter 12. Approach to Globus Pallidus Internal
• Regional Anatomy of the Globus Pallidus Internal (GPi) Segment
• Adverse Effects Resulting from the Position ...

  Biographie:
  and new technological advances that make pre-existing theories of pathophysiology obsolete. Key Features of the Second Edition Include - Highlights post-operative deep brain stimulation...

  Sommaire:
  Dr. Montgomery is a Movement Disorders Neurologist with a special interest in Parkinson's disease. He has conducted research in motor neurophysiology, particularly the role of the basal ganglia-thalamic-cortical system and the pathophysiology of Parkinson's disease for over 40 years. For the last 20 years, he has focused on deep brain stimulation in its clinical use and its underlying physiological mechanisms....