The Anatomical Substrate for Telencephalic Function - Veenman, C. Leonardus

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Résumé :
This study is based on the thesis that the purpose of the telencephalon is to enable an animal to make decisions in new situations. The authors propose a model for the performance of this function based on the combination of a selection system with a sensory-motor system. The elements of the model were studied in Xenopus laevis and subsequently compared with the organization of the elements in other vertebrates. This model explains the effects of forebrain lesions and experimental physiological data, and it is generally applicable. It provides a tool for understanding the brain as such as well as a framework to which other input/output functions can be attached.

Sommaire:
1 Introduction: Theoretical Basis for Telencephalic function.- 1.1 Telencephalic function.- 1.2 Dual Sensorimotor and Selection System.- 1.3 Position of the Pallium.- 1.4 Working Hypotheses.- 1.5 Choice of Animal.- 1.6 Methods Employed.- 2 Methods and Results: Study of Prosencephalic Connectivity and Structural Organization.- 2.1 Extra-experimental Procedures.- 2.2 Experimental Procedures.- 2.3 Horseradish Peroxidase Labeling.- 2.4 Display of the Forebrain and Injection Sites.- 2.5 Horseradish Peroxidase Injections in the Pallium (1-12).- 2.6 Horseradish Peroxidase Injections in Extrapallial Telencephalic Areas (13-16).- 2.7 Horseradish Peroxidase Injections in Extratelencephalic Regions (17-22).- 3 Methods and Results: Electron Microscopic Study of HRP-Labeled Elements.- 3.1 Preparation of the Electron Microscopic Material.- 3.2 Electron Microscopic Material.- 3.3 Conclusions.- 4 Methods and Results: Distributions of Opioids, Substance P, and Serotonin.- 4.1 Immunohistochemistry.- 4.2 Distributions.- 4.3 Conclusions.- 5 Discussion: Hodological, Functional, and Comparative Concepts.- 5.1 Connectivity of the Telencephalon.- 5.2 Midline Crossing Connections.- 5.3 Function of the Pallium.- 5.4 Comparisons with Other Vertebrates.- 5.5 Conclusions.- 6 Summary.- References.