Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine - Kane, Michael D
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Présentation Pharmacogenetics, Kinetics, And Dynamics For Personalized Medicine Format Broché
- Livre Médecine, Pharmacie, Paramédical, Médecine vétérinaire
Résumé :
Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine provides a primer to understand pharmacogenetics (the study of genetic factors that influence how a drug works) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, that is, personalized medicine. Through specific drug examples, this resource explores how the genetic constitution of an individual may lead to the need for an altered dose or in some cases alternative drug therapy. Real-world cases highlight the specific relationships between genetics, drug action, and the body's response as well as adverse drug reactions, altered metabolism, and drug efficacy. Ethical issues concerning pharmacogenomics and study design are also discussed in this concise overview....
Biographie: Associate Professor of Computer Technology Department of Computer and Information Technology, Purdue University College of Technology Professor of Pharmacology and Dean, Ohio Northern University Raabe College of Pharmacy Assistant Professor of Pharmacology, Ohio Northern University Raabe College of Pharmacy
Sommaire:
Dr. Kisor is Professor and Chair of the Department of Pharmaceutical and Biomedical Sciences at the Raabe College of Pharmacy at Ohio Northern University. Kisor received his Bachelor of Science degree in Pharmacy from the University of Toledo and his Pharm. from The Ohio State University. He completed a fellowship in Therapeutic Drug Monitoring and Pharmacokinetics at Ohio State. Kisor came to ONU from Burroughs Wellcome Co., now GlaxoSmithKline, where he was a research scientist in Pharmacokinetics & Drug Metabolism, working mostly on the development of purine analog anti-leukemia drugs, including the drug nelarabine, a derivative of guanine, one of the building blocks of life, that was marketed in the U.S. in 2005. His focus at ONU has been teaching pharmacokinetics and relating genetics to pharmacokinetics. He has integrated pharmacogenetics into the pharmacokinetic subject matter since 1998. He is a member of the American Pharmacists Association (APhA), the American Association of Colleges of Pharmacy (AACP), the National Coalition for Healthcare Provider Education in Genetics (NCHPEG), and the Personalized Medicine Coalition (PMC) and is the advisor for the ONU Student Chapter of the PMC....