Practical Bioinformatics - Michael Agostino
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Présentation Practical Bioinformatics de Michael Agostino Format Broché
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Résumé : Practical Bioinformatics is specifically designed for biology majors, with a heavy emphasis on the steps required to perform bioinformatics analysis to answer biological questions. It is written for courses that have a practical, hands-on element and contains many exercises (for example, database searches, protein analysis, data interpretation) to complement the straightforward and practical topics. The chapters are focused on DNA, RNA, and protein sequence analysis?frequently performed subsets of the field of bioinformatics?taking the reader through the commonly asked question ?what can I learn about this sequence??
Sommaire: 1. Introduction to Bioinformatics and Sequence Analysis A sample chapter and detailed table of contents are available at www.garlandscience.com/practical-bioinformatics.
2. Introduction to Internet Resources
3. Introduction to the BLAST suite and BLASTN
4. Protein BLAST: BLASTP
5. Cross-Molecular Searches: BLASTX and TBLASTN
6. Advanced Topics in BLAST
7. Bioinformatics Tools for the Laboratory
8. Protein Analysis
9. Explorations of Short Nucleotide Sequences
10. MicroRNAs and Pathway Analysis
11. Multiple Sequence Alignments
12. Browsing the Genome
This is one of the most well written and well organized books on bioinformatics that I have come across. The chapters and concepts are arranged in order of complexity and the writing is easy to understand. This is an excellent introductory book for bioinformatics, yet it contains enough detail to help both a serious researcher as well as a beginner in the field. -Science Books & Film This textbook would be useful to any biologist, as its chapters span RNA sequencing to protein analysis to miRNA target prediction. It is hard to think of a database currently available online on which this text does not include a detailed tutorial...it made bioinformatics appealing to learn about, as some pages contained highlighted boxes of interesting facts about the history of sequencing, biology, or various discoveries...Practical Bioinformatics will be invaluable to the general researcher or student... -Yale Journal of Biology and Medicine The book is well laid out, focusing initially on finding and manipulating single DNA or protein sequences from a number of different databases...Anyone who deals with biochemical data would find this work of great value. Even an absolute novice to bioinformatics would, with a little practice, be able to retrieve and manage data. -The Biologist This is exactly the kind of text that I have been looking for to support my bioinformatics teaching... To minimise the entry barrier for using bioinformatics, the author uses only free Web-based tools...There is really good coverage of the many flavours of BLAST, multiple sequence alignments and common tools for DNA and protein sequence analysis, with clear and interesting worked examples and critical analysis of outputs. - Microbiology Today
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