Chiral Separations -

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Résumé :
This fully updated volume focuses on analytical separations by chromatographic and electrophoretic techniques, providing some overview along with a multitude of practical applications. Examination of the application of sensors for enantiodifferentiation as well as chapters on the analysis of analyte-selector complexes by NMR spectroscopy and molecular modeling have been included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and practical, Chiral Separations: Methods and Protocols, Fourth Edition serves as a helpful guide for analytical chemists working on stereochemical problems in the fields of pharmacy, chemistry, biochemistry, food chemistry, molecular biology, forensics, environmental sciences, or cosmetics in academia, government, or industry....

Biographie:

Recognition Mechanisms of Chiral Selectors: An Overview.- Enantioseparation by Thin Layer Chromatography.- Enantioseparations by Gas Chromatography Using Porous Organic Cages as Stationary Phase.- Chiral Gas Chromatography in Wine Analysis.- Polysaccharide-Based Chiral Stationary Phases for Enantioseparations in Liquid-Phase Techniques: An Overview.- Polysaccharide-Based Chiral Stationary Phases Made with Superficially Porous Silica.- Analysis of Isomers of New Chiral Psychoactive Substances Using Enantioselective High-Performance Liquid Chromatography-Mass Spectrometry.- Preparative Chiral Resolution of Synthetic Cathinones Using Polysaccharide-Based Chiral Stationary Phases.- Enantioselective Analysis of Chiral Agrochemicals with High-Performance Liquid Chromatography.- Application of Chiral HPLC to Medicinal Chemistry-Related Problem Solution.- Chiral High-Performance Liquid Chromatography (HPLC) in Targeted Metabolomics.- Two-Dimensional LC-MS/MS Determination of Chiral Amino Acids in Real-World Samples.- Macrocyclic Glycopeptide-Based Chiral Stationary Phases Applied in Enantioselective Liquid Chromatographic Analyses: An Overview.- Separation and Analysis of Chiral Compounds by Nano-Liquid Chromatography Using Glycopeptide Antibiotics.- Cinchona Alkaloid-Based Zwitterionic Chiral Stationary Phases Applied for Liquid Chromatographic Enantiomer Separations: An Overview.- Fundamental Kinetic Studies for Understanding Chiral Separations in High-Performance Liquid Chromatography.- Molecularly Imprinted Polymer-Based Chiral Stationary Phases for Chromatographic Enantioseparation.- Applications of Chiral Supercritical Fluid Chromatography on Polysaccharide-Based Stationary Phases.- Cyclodextrins as Chiral Selectors in Capillary Electromigration Techniques.- Chiral Separation in Capillary Electrophoresis Using Cyclodextrins in Combination with Hydrophobic Deep Eutectic Solvents.- Application of Amino Acid-Based Chiral Ionic Liquids for Enantioseparation in Capillary Electrophoresis.- Application of Enantioselective Capillary Electrophoresis in Forensic Analysis.- Chiral Separations by Using Capillary Electrochromatography: An Overview.- Molecularly Imprinted Polymer-Based Electrochemical Chiral Sensors.- Nuclear Magnetic Resonance Spectroscopy Experiments to Investigate Separations of Enantiomers by Capillary Electrophoresis.- Application of Molecular Modeling to Capillary Electrophoresis Enantioseparations Promoted by Cyclodextrin-Based Chiral Selectors.