Applied Metallomics -

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Résumé :
Applied Metallomics

A groundbreaking survey of a field that unites the sciences

The metallome of a cellular compartment, such as an enzyme, is the variety and arrangement of its metal ions. Metallomics is the multidisciplinary study of the metallome and its many important interactions with biological molecules and systems. It exists at the intersection of biochemistry and materials science, offering crucial insights into biological processes in which iron, for instance, plays a pivotal role.

Applied Metallomics is an up-to-the-minute overview of research developments in metallomics, offering both analysis and applications in a vast array of scientific and industrial areas. Moving freely between material science, environmental science, health science, and more, it offers a comprehensive survey of this interdisciplinary research area. As the field of metallomics continues to develop and its applications expand, this book will only be a need of the hour

Applied Metallomics readers will also find:

• Detailed treatment of nanometallomics, environmetallomics, agrometallomics, and many more
• Coverage of machine learning and artificial intelligence techniques with applications in metallomics
• An author team with vast international research experiences

Applied Metallomics is ideal for researchers in many areas touched by metallomics, that include chemistry, biochemistry, biotechnology, bioinorganic chemistry, and more....

Biographie:

Yu-Feng Li, PhD, is the Acting Associate Director of the CAS-HKU Joint Laboratory of Metallomics on Health and Environment, Beijing, China. He is a past recipient of the Chinese Academy of Sciences Lu Jiaxi Young Talent Award and the Young Scientist Award of the First International Symposium on Metallomics, and has published extensively on metallomics and related subjects.

Hongzhe Sun, PhD, is the Director of the CAS-HKU Joint Laboratory of Metallomics on Health and Environment, Hong Kong, China. He has published very widely on metallomics and related subjects, and his past awards include the UC Berkeley Earl L. Muetterties Memorial Lectureship and the Croucher Senior Research Fellowship....

Sommaire:

Foreword xv

Preface xvii

1 Introduction 1
Yu-Feng Li and Hongzhe Sun

1.1 A Brief Introduction to Metallomics 1

1.2 Key Issues and Challenges in Metallomics 3

1.3 About the Structure of this Book 4

2 Nanometallomics 11
Hongxin Xie, Liming Wang, Jiating Zhao, Yuxi Gao, Bai Li, and Yu-Feng Li

2.1 The Concept of Nanometallomics 11

2.2 The Analytical Techniques in Nanometallomics 12

2.3 The Application of Nanometallomics in Nanotoxicology 17

2.4 Conclusions and Perspectives 21

3 Environmetallomics 33
Lihong Liu, Ligang Hu, Baowei Chen, Bin He, and Guibin Jiang

3.1 The Concept of Environmetallomics 33

3.2 The Analytical Techniques in Environmetallomics 34

3.3 The Application of Environmetallomics in Environmental Science and Ecotoxicological Science and the Perspectives 43

4 Agrometallomics 49
Xuefei Mao, Xue Li, Tengpeng Liu, and Yajie Lei

4.1 The Concept of Agrometallomics 49

4.2 Analytical Techniques in Agrometallomics 52

4.3 Application and Perspectives of Agrometallomics in Agricultural Science and Food Science 127

5 Metrometallomics 153
Liuxing Feng

5.1 The Concept of Metrometallomics 153

5.2 The Analytical Techniques in Metrometallomics 154

5.3 The Application of Metrometallomics in Life Science and the Perspectives 159

6 Medimetallomics and Clinimetallomics 193
Guohuan Yin, Ang Li, Meiduo Zhao, Jing Xu, Jing Ma, Bo Zhou, Huiling Li, and Qun Xu

6.1 The Concept of Medimetallomics and Clinimetallomics 193

6.2 The Analytical Techniques in Medimetallomics and Clinimetallomics 195

6.3 The Application of Medimetallomics and Clinimetallomics in Medical and Clinical Science and the Perspectives 204

7 Matermetallomics 237
Qing Li, Zhao-Qing Cai, Wen-Xin Cui, and Zheng Wang

7.1 The Concept of Matermetallomics 237

7.2 The Analytical Techniques in Matermetallomics 243

7.3 The Application of Matermetallomics in Material Science and the Perspectives 256

8 Archaeometallomics 265
Li Li, Yue Zhou, Sijia Li, Lingtong Yan, Heyang Sun, and Xiangqian Feng

8.1 The Concept of Archaeometallomics 265

8.2 The Analytical Techniques in Archaeometallomics 266

8.3 The Application of Archaeometallomics in Archaeological Science 269

8.4 Summary and Perspectives 279

9 Metallomics in Toxicology 285
Ruixia Wang, Ming Gao, Jiahao Chen, Mengying Qi, and Ming Xu

9.1 Metallomic Research on the Toxicology of Metals 285

9.2 Recent Progresses in Understanding the Health Effects of Heavy Metals 287

9.3 Knowledge Gaps, Challenges, and Perspectives 297

10 Pathometallomics: Taking Neurodegenerative Disease as an Example 311
Xiubo Du, Xuexia Li, and Qiong Liu

10.1 Introduction to Pathometallomics 311

10.2 Application of Pathometallomics in Neurodegenerative Diseases 314

10.3 The Perspectives of Pathometallomics 338

11 Oncometallomics: Metallomics in Cancer Studies 349
Xin Wang, Chao Li, and Yu-Feng Li

11.1 Introduction to Oncometallomics 349

11.2 The Application of Oncometallomics in Cancer Studies 351

11.3 The Metallome that Involved in the Occurrence and Development of Cancer 355

11.4 Conclusions and Perspectives 356

12 Bio-elementomics 363
Dongfang Wang, Jing Wu, Bing Cao, Lailai Yan, Qianqian Zhao, Tiebing Liu, and Jingyu Wang

12.1 Introduction 363

12.2 Basic Laws of Bio-elementomics 364

12.3 Rare-Ea...