Using IPSCS to Study ALS Development - Rajpurohit, Chetan Singh

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Résumé :
The book provides a thorough understanding of iPSC technology, its advantages, and its potential for modeling ALS, which is a complex and devastating neurodegenerative disorder affecting the motor neurons. The author explains the use of iPSCs as a tool to generate disease-specific models for ALS and how these models can aid in the identification of novel biomarkers, drug targets, and potential therapies for ALS. Furthermore, the book highlights the role of early developmental stages in ALS pathogenesis and the potential of iPSCs in studying this association. The author provides a detailed overview of the current knowledge of ALS development and the latest advancements in iPSC technology that have led to the generation of patient-specific motor neurons and astrocytes. The book is an excellent resource for researchers, clinicians, and students who are interested in understanding the molecular mechanisms of ALS and the potential of iPSCs in developing effective therapies for this debilitating disease. With its clear and concise language and comprehensive coverage of the topic, Using iPSCs to study ALS development is an essential read for anyone seeking to deepen their understanding of this complex disorder....